https://www.mphartlab.com/home daily 1.0 2023-08-24 https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1568820964809-7LYONSC3YQH5W3V37YIY/banner1.jpg Home https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1566392388944-GDKHFKONG2FS5R8YPUY3/connectome2.jpg Home White matter pathways in human brain, ~90 billion neurons (adapted from humanconnectomeproject.org). Ball and stick model of every neuron in C. elegans, 302 neurons (openworm.org) https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1566392058075-GAGGD3TNXS72QTW7YL17/DVB+circuit+behavior.png Home One example of a ‘simple’ circuit - cartoon showing the DVB neuron and neurons/muscles it makes synaptic connections to that are involved in regulation of one step of the spicule protraction behavior, shown on right. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/3111d87e-3115-4e95-bc22-648bed15bc4c/Screen+Shot+2023-08-18+at+1.12.41+PM.png Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1ca7e3c4-be62-4a88-a092-894a95534271/Screen+Shot+2023-08-18+at+1.01.21+PM.png Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/dffce9f3-40e1-482b-909b-973a0b8226d7/nlg-1-food-3.gif Home - Make it stand out on food baseline activity https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/04c05a78-e53d-47b3-bb16-4f7a36dbad6f/nlg-1-no-food-3.gif Home - Make it stand out no food hyperactivity https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1566391928563-4EP91S1JE2XPJXVJVK1Q/nrxn+and+genes.png Home Cartoon showing a few synaptic proteins conserved from humans to C. elegans, including neurexins, neuroligins and shanks (all with multiple genes in humans and only a singular ortholog in C. elegans). Protein domain structure of three forms of human neurexin compared with the singular C. elegans ortholog, nrx-1. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1562179242153-DHIGIHV3Y42M02TXB9TX/HartLogo+copy.gif Home - Seeking candidates for graduate and undergraduate positions - see contact page https://www.mphartlab.com/publications daily 0.75 2026-06-25 https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1562163023042-L8S6EOSX6WAU0JL5X8H8/HartLogo+copy.gif Publications - Click Here for PubMed list of all publications https://www.mphartlab.com/labmembers daily 0.75 2026-07-17 https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/a5acd6b6-5910-4a4f-9432-8295d783d8bf/IMG_9708.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/9bddbe97-827c-44ff-abae-e143938caa78/IMG_5280.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/edba3813-12a3-4db5-af50-0c46d7cf061d/IMG_5434.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/2d04ae49-82d9-4928-bfed-d8d2f3dbcd9c/Hart+MP.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1596059112741-Y5EUAAT66VL2DEWI9EEW/Screen+Shot+2020-07-29+at+5.32.05+PM+copy.png Lab Members Artist: Daniel Quasar https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/ad8bde33-aaa0-4b86-87a8-f1f028b46080/Dustin_profile.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1d604300-b29b-458c-9905-32a9c97c8d6d/PXL_20231229_192930113%7E2.jpg Lab Members https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1606930554986-SIT4O9UVT3PJWAFIGG0Y/profile+picture.png Lab Members https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/edfdfa87-58ed-4e16-98e2-8242c6a5042d/IMG_7958+%281%29.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/c83bc5e2-4de1-4ce3-89a7-f0c271f8a165/Screen+Shot+2023-08-23+at+4.59.56+PM.png Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/43dad395-4d0e-4d69-a28d-785a9fa1d687/DSC_0429.JPG Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/9189a97c-8411-4430-ace6-c8620368d30c/IMG_1957.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/84153165-e3ef-44d0-a30a-a0552f5e0b6d/Screen+Shot+2024-03-04+at+12.44.52+PM.png Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/8df0cf07-051f-4026-8503-f6ab889c4052/6DD81545-057C-419C-90E4-B796C10F2201+%281%29.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1566409299113-RR5FPAXOZSWJBTY8GCQU/elegansgif.gif Lab Members https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1596057393212-EAH7NWO8JGS7T3VIF9CG/image0.jpg Lab Members Artist: Sammy Katta - https://sammykatta.com/diversity https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/124a3de2-b520-460d-b869-aa1be9199fd3/IMG_0040.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/3ef39f25-39eb-4942-a724-1f333488ebfc/lab+summer+2021.png Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/944fe82f-e465-46b0-8c15-1a89bcce8639/IMG_1521.jpg Lab Members - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.mphartlab.com/contact-us daily 0.75 2024-11-11 https://www.mphartlab.com/research daily 0.75 2023-08-18 https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1561579898271-CTX4YJ19KPGJ68YAI2VI/website5.jpg Research https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1566393865669-5H3J4PLW329R7BPG3QVK/DVB+circuit+etc.png Research Cartoons of DVB neuron in each sex of C. elegans, with wiring diagram of DVB synaptic connections within each respective sex-specific circuit based on EM reconstruction (wormwiring.org). https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1566416906762-FC6BMEUXTB9I53N3NXPU/dvb+time-01.png Research The GABAergic DVB neuron in males at day 1, 3, and 5 of adulthood showing progressive neurite outgrowth (arrows)(lim-6::wCherry), with new neurites making additional pre-synaptic connections (lim-6::gfp::rab-3). https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1566395835239-QPJL9K70E60HLFG4BR5Z/newfig1-01.png Research C. elegans can be utilized as a model to study how mutations in autism-associated gene orthologs may impact DVB neuron morphology and circuit plasticity, as well as behavioral phenotypes that implicate additional functions in novel neuronal circuits. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/1562174122064-I9FZFUMAXLBQIQ7L4F91/HartLogo+copy.gif Research - 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ELEGANS POPULATIONS (LEFT AND RIGHT) AND SYNAPSES (CENTER). https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/9a3b16d2-5787-4ae9-b673-5d7b7e2b797d/KZ2024.png SciArt KZ2024 (MPH). METAL PLATE CUTOUT OF A CONFOCAL STACK TAKEN OF THE DVB NEURON MOUNTED ON WOOD PANEL. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/f1e025b5-2ecd-4768-9afb-b16fea70cbb2/Vote+square.png SciArt - Make it stand out VOTE (MHC). Acrylic on paper. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/06e38a56-c337-421d-bcf2-18b757f97adc/BLB2024+1.png SciArt - Make it stand out BLB2024 (MPH). Photo prints on foam board with relief and sunken C. elegans with neurons from confocal image of nrx-1 expression. Repeating patterns made from octopamine chemical structure or WorMotel image. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/72fe519a-db32-498c-92bf-5fee5992d6a6/BLB2024+2.png SciArt - Make it stand out BLB2024 (MPH). Photo prints on foam board with relief and sunken C. elegans with dopamine neurons from confocal image. Repeating patterns made from dopamine chemical structure or WorMotel image. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/826a176e-494f-4c5e-9935-364b2c670e08/Worm+in+the+lab.png SciArt JUST ANOTHER WORM IN THE LAB (MHC). Acrylic on canvas board. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/613b80ff-da43-44ce-adbe-02a60fdbf671/Food.png SciArt FOOD (MPH). Acrylic on canvas board. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/3630bcf6-4cbd-48ce-908a-ffb617e41321/SMV2026.png SciArt - Make it stand out SMV2026 (MPH). PINK CLAY SCULPTURE IN SHAPE OF DVB NEURON WITH EXTENDED NEURITES PLACED IN GLASS AND METAL TERRARIUM CUBE WITH PLANTS (Fittonia Albivenis Red, Lemon Button Fern, Hedera helix 'Itsy-Bitsy', Humata Tyermanii (White Rabbit's Foot Fern), Begonia bipinnatifida, Pilea libanensis (Silver sprinkles)). https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/93c6088a-9b97-4c14-9d82-b0a9b97be27b/JP2026.png SciArt - Make it stand out JP2026 (MPH). ACRYLIC STAMPED ON CANVAS WITH BLACK STAIN STAMP OVERLAY. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/a2f51bd0-c572-46f6-9612-5ababd7f74e8/IMG_1769.png SciArt - Make it stand out Left: WRH2026 (MPH) Center: DH2026 (MPH) Right: JP2026 (MPH) https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/20c1ee31-af18-464e-a1a0-86244c2b57fd/WRH2026.png SciArt - Make it stand out WRH2026 (MPH). ACRYLIC STAMPED ON CANVAS WITH BLACK STAIN STAMP OVERLAY. https://images.squarespace-cdn.com/content/v1/5d126b46818118000135f360/fecad5cf-bb1b-4ce4-ba13-2e2218756041/DH2026.png SciArt - Make it stand out DH2026 (MPH). ACRYLIC STAMPED ON CANVAS WITH BLACK STAIN STAMP OVERLAY.